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排序方式: 共有410条查询结果,搜索用时 46 毫秒
1.
实验研究了平顶飞秒激光经圆锥透镜后在熔融石英中的成丝及超连续辐射.与高斯飞秒激光的成丝对比发现,平顶飞秒激光可以获得在圆锥透镜焦深区域内强度分布更为均匀的等离子体细丝,这一特征更有利于飞秒激光在固体介质中进行微纳加工等领域的应用.并且,在不损伤熔融石英的条件下,平顶飞秒激光成丝可以获得更高能量、更高转换效率的超连续辐射,这是因为若产生光强相近的细丝,平顶飞秒激光所需的初始激光能量更高,此激光能量下产生的细丝长度更长、均匀性更好. 相似文献
2.
参照相关标准,对聚变装置真空室超压保护系统(VVPSS)中爆破片进行了选型。结合VVPSS的工作要求,完成了爆破片的设计计算,初步得到爆破片直径为882mm,厚度为1mm。利用有限元分析软件对多种型号爆破片进行结构分析比较,最终选用了反拱环向开缝型爆破片。对最终选定的爆破片进行优化设计,使其达到设计要求。 相似文献
3.
Vinod K. Ahirrao Rajiv A. Jadhav Suyog N. Vaidya Sachin S. Bhagwat Ravindra D. Yeole Mahesh V. Patel 《Biomedical chromatography : BMC》2022,36(6):e5354
Antibiotic susceptibility test (AST) discs are used as an in-vitro diagnostic tool to select the appropriate antibiotic to treat an infection. Generally, the concentration of the drug loaded on to the AST discs is measured by studying its activity against quality control organisms. This methodology has several limitations—it is time consuming, requires trained manpower, has a wider acceptance criteria of zone of inhibitions—causing ambiguity in judging smaller variations in drug concentration. To overcome these issues, we have developed and validated high-performance liquid chromatographic (HPLC) methods for the determination of strength of AST discs for in-house researched antibiotics, namely Levonadifloxacin/WCK 771, Nafithromycin/WCK 4873, Cefepime-Tazobactam/WCK 4282, and Cefepime-Zidebactam/WCK 5222. The drugs were extracted from the AST discs using an appropriate solvent. The developed methods are simple, accurate, precise, reproducible, rugged, and robust. They are efficient in terms of time, and can be easily conducted in a quality control laboratory during release as well as stability evaluation of AST disc. Application of HPLC methods for the determination of strength of AST discs ensures flawless quality and, consequently, a better selection of drugs to treat bacterial infections in clinics. 相似文献
4.
探讨DCE-MRI参数及IFIT1基因对腰椎间盘突出症(LDH)患者椎间盘退变(IDD)程度的评估价值。随机选取确诊的66例LDH患者作为研究对象,根据改良Pfirrmann分级法将患者分为2组:轻中度IDD(Ⅰ~Ⅲ级)组(46例)和重度IDD(Ⅳ~Ⅴ级)组20例。通过DCE-MRI检查考察患者的K-trans值,采用日本骨科学会评分(JOA)评估腰椎功能,采用视觉模拟评分法(VAS)评估腰部疼痛,采用RT-PCR检测外周血单个核细胞(PBMC)中IFIT1的mRNA表达。轻中度IDD组的K-trans值显著低于重度IDD组。轻中度IDD组患者PBMC中的IFIT1 mRNA相对表达量显著低于重度IDD组。K-trans值与PBMC中的IFIT1 mRNA水平和VAS评分正相关,与JOA评分负相关(P<0.05)。PBMC中的IFIT1 mRNA水平与VAS评分正相关,与JOA评分负相关(P<0.05)。K-trans值和PBMC中的IFIT1 mRNA水平联合诊断重度IDD的AUC值、敏感性和特异性分别为0.991、91.3%和100.0%,AUC值和特异性均高于单独诊断。DCE-MRI检查中的K-trans值联合PBMC中的IFIT1 mRNA水平可用于LDH患者IDD程度的诊断。 相似文献
5.
6.
选择腰椎间盘突出症(LDH)患者60例,分为轻度退变组、中度退变组、重度退变组。患者均行MRI检查,比较3组的MRI参数,包括髓核(NP)区、纤维环(AF)区T2值。检测比较发现,3组LDH患者NP区、AF区T2值间存在明显差异,且与腰椎功能评分(JOA)呈正相关,与腰部疼痛评分(VAS)呈负相关(P<0.05)。NP区、AF区T2值联合鉴别轻中度、中重度椎间盘退变程度的AUC大于各指标单一鉴别,具有较高评估效能。因此,MRI参数评估LDH患者椎间盘退变程度方面具有良好价值,可为临床明确患者病情提供重要参考。 相似文献
7.
Poliana Cristina Spricigo Banny Silva Barbosa Correia Karla Rodrigues Borba Isabela Barroso Taver Guilherme de Oliveira Machado Renan Ziemann Wilhelms Luiz Henrique Keng Queiroz Junior Angelo Pedro Jacomino Luiz Alberto Colnago 《Molecules (Basel, Switzerland)》2021,26(12)
The cambuci is a native Brazilian fruit from the Atlantic Forest biome. A soft and astringent pulp, a green color, and a sweet aroma are its main characteristics. Classical food quality attributes (fresh fruit mass, fruit height, diameters, total soluble solid, titratable acidity, and ratio) and the metabolic profile from ten accessions from three different locations were analyzed herein by analytical methods (refractometry and neutralization titration) and nuclear magnetic resonance spectroscopy. Concerning sugar content, sucrose was the predominant compound, with glucose and fructose alternating in second, depending on the accession. Citric acid was the most relevant acid, followed by shikimic and quinic acids in quite variable amounts. These three main acids vary in amounts for each accession. Ascorbic acid content emerges as an important quality attribute and makes this fruit nutritionally attractive, due to values comparable to those contained in citric fruits. The main amino acids identified in cambuci were glutamic acid individually or in comprising the tripeptide glutathione (glutamic acid, cysteine, glycine). The quality diversity of the evaluated accessions suggests the potentiality of cambuci use in future breeding programs. 相似文献
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9.
The solutions of the continuity equation and the equations of motion of the flow in the vicinity of a rotating disk have been established for an Ostwald fluid under steady-state conditions and in modulated flow around a mean value. Under steady-state conditions, the kinematics of the flow is scarcely dependent on the rheological parameters close to the disk, however, for n < 1 long-range effects have been put forward. For modulated flow, in the high-frequency range, a behaviour very different from that observed for a Newtonian fluid was found. In the low-frequency range an asymptotic solution has been proposed which is of special interest in mass transfer problems.Presented at the Second Conference of European Rheologists, Prague, June 17–20, 1986 相似文献
10.
Friction-induced vibration of a two-degree-of-freedom mass-damper-spring system interacting with a decelerating rigid strip
is investigated. The friction law is approximated by an analytical function to facilitate the analyses and numerical integrations.
It is shown that, after a quasi-harmonic transient period, accompanied by viscous energy dissipation, a short period of intensive
‘creep-slip’ vibration occurs, which generates a series of ‘micro-impacts’ on the strip. Because of the impulsive character
of such kind of loading, its Fourier spectrum is rich and quite broadband. Using an averaging technique, the ‘normal form’
equations of motion show that the out-of-phase vibration mode absorbs more energy from the decelerating strip when its natural
frequency satisfies certain resonance conditions. The study is then applied to an automotive disc brake model to gain useful
insight into the generation of squeal. It is shown that the out-of-phase creep-slip vibration (in the longitudinal direction)
of the brake pads generates an impulsive bending moment on the decelerating strip (disc rotor). This impulsive load may be
considered as a possible source for brake squeal. The technique developed in this paper may be extended to other ‘squealing
systems’ including models for geophysical faults (earthquakes). 相似文献